FEATURES & BENEFITS OF Dr.PRP® (DISCOURSE) PRP ("Platelet Rich Plasma") is nothing but autologous blood with concentrations of platelets above baseline levels and contain at least seven growth factors. Normal blood contains only 6% platelets. However, in PRP, there is a concentration of 94% platelets, which translates to a powerful growth factor "cocktail" with a variety of growth factors and cytokines. This stimulates cellular proliferation and tissue regeneration to dramatically accelerate healing. And since the platelets come from the patient’s own blood, there is absolutely no possibility of infection or other side effects. The only precaution you need to take is to stop any anti-inflammatory medications while administering PRP. OVERVIEW Dr.PRP® Separation Kit: A Versatile Patented System for Safe and Effective PRP Regenerative Therapy Dr.PRP® is a medical kit designed for fast & efficient PRP separation. Dr.PRP® kit is promised to drive a perfect concentration of Platelet Rich Plasma (PRP) every time use. Concentration of platelets determines the amount of growth factors per blood sample, which in turn affects the speed of healing. So for consistently efficient PRP treatments with faster results, you can count on Dr. PRP’s patented one-step platelet separation kit. Platelets (together with the liquid plasma in PRP) are body’s natural response to injuries and contain a large amount of growth factors that induces accelerated tissue regeneration and proliferation. FEATURES & BENEFITS OF Dr.PRP® (DETAILS) SAFETY Dr.PRP® Kit uses biocompatibility certified materials and the parts undergo gamma-ray sterilization according to ISO 13485 standards. ONE STEP SIMPLICITY Dr.PRP® Kit is compatible with most common centrifuges. Chances are it will work with your existing centrifuge as well so no new investment is needed. SPEED & CONVENIENCE The Buffy Coat Layer can be easily and accurately identified by naked eye so you’ll have precise sample of highly concentrated PRP. HIGH CONCENTRATION Dr. PRP® ensures you’ll have a high concentration of Platelets in your blood plasma sample thanks to second centrifugation. NEW PATENTED DESIGN Dr. PRP’s patented design ensures you get a large amount of growth factors from your patient’s blood plasma samples. This means fast, effective healing and happy customers for you. FOR ALL CENTRIFUGES Dr.PRP® Kit is compatible with most common centrifuges. Chances are it will work with your existing centrifuge as well so no new investment is needed. EASY EXTRACTION OF PRP Dr. PRP® uses only a single tube for the whole PRP separation process so you can get more treatments done in less amount of time. Focus on the things that matter, not on processes. PRP & STEM CELL THERAPY ASC (Adult Stem Cell Therapy) Stem cells are the repairmen of the body. The type of adult stem cell that is most often seen in research as being associated with tissue repair is a mesenchymal stem cell (MSC). MSC are readily available in Fat and Bone Marrow. These mesenchymal stem cells usually travel to the injured areas via the blood stream. If the injured area has a poor blood supply like joints, meniscus tissue, rotator cuff and other tendon injuries, then these areas typically do not heal well on their own due to the poor blood supply channel. ASC (Adult Stem Cell Therapy) can be harvested and injected into our own degenerated joints and ligaments. Upon contact with the degenerated joint surfaces or other damaged tissues, the stem cells are able to determine the damaged cells (a process called ‘homing’) and in turn, become new, healthy versions of those cells (a process called ‘differentiation’). Injecting these injured areas with stem cells leads to healing, decreased pain and improvement in function. “Stem Cells need to be directed and this is done by Platelet-Rich Plasma (PRP)”. Once introduced back into the body, the growth factors, cytokines and signaling proteins from PRP tell the stem cells where to go and what to do and what to transform into. “The growth factors and cytokines from PRP are the directors. Think of stem cells as the construction team and the PRP as their supervisors. ADIPOSE DERIVED STEM CELLS (ADSC) Fat is very rich in stem cells; primarily mesenchymal stem cells. Fat harvesting for ADSC therapy is done with a very simple process called lipoaspiration. It is important to understand that lipoaspiration is vastly different from liposuction. Liposuction is performed by a plastic surgeon in a surgical suite using general anesthesia or sedation. Liposuction removes a very large volume of fat and is intended for a cosmetic result. BONE MARROW ASPIRATE CONCENTRATE (BMAC) Bone marrow contains stem cells; both mesenchymal and hematopoietic stem cells. Bone marrow is harvested from the hip (and sometimes from the shin bone called the Tibia) using local anesthetic and a specialized needle. It is important to understand that bone marrow harvesting for BMAC is vastly different from bone marrow harvesting for transfusion for cancer therapies. In bone marrow harvesting for transfusion, a hematologist, oncologist, or surgeon removes a very large amount of bone marrow. BMAC requires only a very small amount of bone marrow. Surprisingly, the procedure is not painful, takes under ten minutes, and causes only mild soreness afterward. It has an excellent safety profile. Mesenchymal stem cells (from fat and bone marrow) differentiate into musculoskeletal tissues such as bone, ligament, muscle, tendon, and joint surface. Hematopoietic stem cells (from bone marrow) differentiate into blood vessels that are needed to nourish musculoskeletal structures and nerves. Platelet rich plasma contains key growth factors that activate the stem cells to generate new, healthy tissue. Therefore, for most procedures, we blend PRP, ADSC, and BMAC.

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